代表性论文

Huamin Liang#, Fengming Zou#, Liyi Fu, Qingwang Liu, Beilei Wang, Xiaofei Liang, Jing Liu, and Qingsong Liu, PEG-Bottlebrush Stabilizer-Based Worm-like Nanocrystal Micelles with Long-Circulating and Controlled Release for Delivery of a BCR-ABL Inhibitor against Chronic Myeloid Leukemia (CML), Pharmaceutics, 2022, 14, 1662.

Rui Zong, Hainan Ruan, Wenzheng Zhu, Peng Zhang, Zhaojun Feng, Chanmin Liu, Shaohua Fan*, Huamin Liang*, Jun Li*, Curcumin nanocrystals with tunable surface zeta potential: Preparation, characterization and antibacterial study. Journal of Drug Delivery Science and Technology, 2022, 76, 103771.

Huamin Liang#, Fengming Zou#, Qingwang Liu#, Beilei Wang, Liyi Fu, Xiaofei Liang, Jing Liu*, Qingsong Liu*, Nanocrystal-loaded liposome for targeted delivery of poorly water-soluble antitumor drugs with high drug loading and stability towards efficient cancer therapy, International Journal of Pharmaceutics, 2021, 120418.

Huamin Liang#, Heini Miranto, Niko Granqvist, Janusz W. Sadowskic, Tapani Viitalab, Bochu Wang*, Marjo Yliperttula*, Surface plasmon resonance instrument as a refractometer for liquids and ultrathin films, Sensors and Actuators B: Chemical, 2010, 149(1): 212-220.

Huamin Liang#*, Jussi-Pekka Tuppurainen, Julia Lehtinen, Tapani Viitala, Marjo Yliperttula, Non-labeled monitoring of targeted liposome interactions with a model receptor surface: Effect of flow rate and water content, European Journal of Pharmaceutical Sciences, 2013, 50(3-4): 492-501.

Niko Granqvist#, Huamin Liang#, Terhi Laurila, Janusz Sadowski, Marjo Yliperttula, Tapani Viitala*, Characterizing Ultrathin and Thick Organic Layers by Surface Plasmon Resonance Three-Wavelength and Waveguide Mode Analysis, Langmuir, 2013, 29(27): 8561-8571.

Tapani Viitala#, Huamin Liang, Mayur Gupta, Thomas Zwinger, Marjo Yliperttula, Alex Bunker*, Fluid dynamics modeling for synchronizing surface plasmon resonance and quartz crystal microbalance as tools for biomolecular and targeted drug delivery studies, Journal of Colloid and Interface Science, 2012, 378(1): 251-259.

Jun Li#*, Huamin Liang, Jing Liu, Ziyuan Wang. Poly (amidoamine) (PAMAM) dendrimer mediated delivery of drug and pDNA/siRNA for cancer therapy, International Journal of Pharmaceutics, 2018, 546: 215-225.

Liyi Fu#, Fengming Zou#, Qingwang Liu, Beilei Wang, Junqing Wang, Huamin Liang, Xiaofei Liang, Jing Liu*, Jinjun Shi*, Qingsong Liu*. An ultra-long circulating nanoparticle for reviving a highly selective BCR-ABL inhibitor in long-term effective and safe treatment of chronic myeloid leukemia, Nanomedicine: Nanotechnology, Biology and Medicine, 2020, 29: 102283.

Tingting Lu#, Jiangyan Cao#, Fengming Zou#, Xixiang Li#, Aoli Wang, Wenliang Wang, Huamin Liang, Qingwang Liu, Chen Hu, Cheng Chen, Zhenquan Hu, Wenchao Wang, Lili Li, Jian Ge, Yang Shen, Tao Ren, Jing Liu, Ruixiang Xia*, Qingsong Liu*. Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML), European Journal of Pharmacology, 2021, 897: 173944.

ElinaVuorimaa-Laukkanen#*, Ekaterina S. Lisitsyna, Tiia-Maaria Ketola, Emmanuelle Morin-Pickardat, Huamin Liang, Martina Hanzlíková, Marjo Yliperttula, Difference in the core-shell dynamics of polyethyleneimine and poly( L-lysine) DNA polyplexes, European Journal of Pharmaceutical Sciences, 2017, 103, 122-127.

Anni E. Sorkio#*, Elina P. Vuorimaa-Laukkanen, Hanna M. Hakola, Huamin Liang, Tiina A. Ujula, Juan José Valle-Delgado, Monika Österberg, Marjo L. Yliperttula, Heli Skottman, Biomimetic Collagen I and IV double layer Langmuir-Schaefer films as microenvironment for human pluripotent stem cell derived retinal pigment epithelial cells, Biomaterials, 2015, 51: 257-269.

Tatu Lajunen#*, Lauri Viitala, Leena-Stiina Kontturi, Timo Laaksonen, Huamin Liang, Elina Vuorimaa-Laukkanen, Tapani Viitala, Xavier Le Guével, Marjo Yliperttulaa, Light induced cytosolic drug delivery from liposomes with gold nanoparticles, Journal of Controlled Release, 2015, 203: 85-98.

承担项目

肿瘤原代细胞可再生技术的原理、工程化，中国科学院合肥物质科学研究院重大项目，2020.09-2023.08（参与）

以病人原代细胞为基础的白血病药物敏感性基因组学基础研究，中国科学院前沿科学重点项目，2017.05-2022.04（参与）

针对RAS和RAF突变实体瘤的pan-RAF抑制剂CHMFL-RAF-128的临床前个性化研究，中国科学院先导专项A类，2019.01-2020.09（参与）

针对FLT3-ITD 阳性急性白血病候选药物CHMFL-FLT3-122的临床个性化研究，中国科学院先导专项A类，2019.01-2020.09（参与）

合肥市领军人才项目，合肥市人才工作领导小组，2019.04-2022.03（主持）

针对胃肠间质瘤的I类靶向新药临床前研究，安徽省科技重大专项，2018.01-2020.12（参与）

针对慢性嗜酸性粒细胞白血病有效靶点激酶PDGFRα的高选择性、高活性个性化先导化合物开发研究，中国科学院先导专项A类，2017.01-2018.12，100万元（参与）

2017安徽省平台引进高层次人才资助，安徽省委组织部（主持）

Printable Pharmaceuticals for Drug Delivery 2011.03-2014.02，芬兰国家技术创新局（参与）

Molecularly Controlled Planar Cell Surface Models: Platform for Targeted Drug and Gene Delivery and Release Optimization，芬兰科学院基金，2010.08-2015.07（参与）