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研究员

研究员

黄青
黄青
职  称: 研究员
所属中心: 医学物理技术研究中心
邮  箱: huangq@ipp.ac.cn
办公地址: 交叉科研南楼516
个人简介

黄青,博士,博导,二级研究员,英国皇家化学学会会士。现在中国科学院合肥物质科学研究院工作。2000年获德国哥廷根大学获理学博士学位;2000-2008在美国从事与物理化学与生物物理研究;2008年回国并入选中国科学院人才计划项目。现任安徽省核学会副理事长、安徽省核农学会主任、安徽省光学学会激光医学副主任等职。

研究领域

主要兴趣集中在物理、化学与生物学交叉领域,研究课题涉及辐射生物物理、生物光谱技术及应用、辐射及低温等离子体生物技术及应用等。迄今在国内外发表论文200余篇,授权专利20余项。主持和承担国家自然科学基金重点与面上项目、安徽省重点研发项目、中科院战略先导以及知识创新工程等项目。

研究成果
1.

代表性论文

(1)

Jialin Li, Shaowei Liu, Amil Aligayev, Hao Jiang, Muhammad, Shenhao Wang, Xin Yu, Jin Tao, Jiaqi Wang, Agnieszka Jastrzębska, Qing Huang*. Dual-mode SERS and colorimetric sensor for lung cancer VOC-biomarker detection using hydrogel patches. Chemical Engineering Journal. 2025; 523: 168343.

(2)

Chao Liu, Qing Huang*. LTP-assisted fabrication of laccase-like Cu-MOF nanozyme-encoded array sensor for identification and intelligent sensing of bioactive components in food. Biosensors and Bioelectronics. 2025; 267: 116784.

(3)

Muhammad Muhammad, Chao Liu, Ge Yang, ChangSheng Shao, Lingzi Xiong, Haiqian Xia, Jamshed Iqbal, Jie Zhan, Feng Qu, Qing Huang*. Early-stage Alzheimer’s disease profiling in blood achieved by multiplexing aptamer-SERS biosensors. Biosensors and Bioelectronics. 2025; 268: 116907.

(4)

Chao Liu, Yi Cao, Qi Xia, Amil Aligayev, Qing Huang*. CoNi-MOF laccase-like nanozymes prepared by dielectric barrier discharge plasma for treatment of antibiotic pollution. Journal of Hazardous Materials. 2025; 493: 138282.                

(5)

Ying Zhang, Zhaoquan Chen, Changsheng Shao, Qing Huang*. Study of the effect of shock wave from a portable pulsed cold air plasma jet device on inactivation of Trichophyton rubrum in nails. Applied Physics Letters. 2024; 124(24): 243701.                

(6)

Muhammad Muhammad, ChangSheng Shao, Qing Huang*. Application of aptamer-SERS nanotags for unveiling the PD-L1 immunomarker progression correlated to the cell metabolic bioprocess. Analytical Chemistry. 2024; 96: 6236-6244.                

(7)

Hangbo Xu, ChaoLiu, Qing Huang* Enhance the inactivation of fungi by the sequential use of cold atmospheric plasma and plasma-activated water: Synergistic effect and mechanism study. Chemical Engineering Journal. 2023; 452(4): 139596.                 

(8)

Lamei Li, Zhu Chen, Adolf Acheampong, Qing Huang*. Low-temperature plasma promotes growth of Haematococcus pluvialis and accumulation of astaxanthin by regulating histone H3 lysine 4 tri-methylation. Bioresource Technology. 2025; 343: 126095.                

(9)

Xinxin Zheng, Qing Huang*. Assessment of the antioxidant activities of representative optical and geometric isomers of astaxanthin against singlet oxygen in solution by a spectroscopic approach. Food Chemistry. 2022; 395: 133584.                

(10)

Di Xu, Muhammad Muhammad, Lin Chu, Qin Sun, Chengyin Shen, and Qing Huang*. SERS Approach to Probe the Adsorption Process of Trace Volatile Benzaldehyde on Layered Double Hydroxide Material. Analytical Chemistry. 2021; 93: 8228−8237.

(11)

Chang Sheng Shao, Xiu Hong Zhou, Yu Hui Miao, Peng Wang, Qian Qian Zhang, and Qing Huang*. In-situ observation of mitochondrial biogenesis as the early event of apoptosis. iScience. 2021; 24: 103038.                

(12)

Chang-Sheng Shao, Xiu-Hong Zhou, Xin-Xin Zheng, Qing Huang*. Ganoderic acid D induces synergistic autophagic cell death except for apoptosis in ESCC cells. Journal of Ethnopharmacology. 2020; 262: 113213.

(13)

Zhigang Ke, Yulong Ma, Zhongjie Zhu, Hongwei Zhao, Qi Wang*, Qing Huang*. Non-thermal hydrogen plasma processing effectively increases the antibacterial activity of graphene oxide. Applied Physics Letters. 2018; 112(1): 013701.

(14)

Zhimin Zhai, Fengqiu Zhang, Xiangyu Chen, Jie Zhong, Gang Liu, Yangchao Tian and Qing Huang*. Uptake of silver nanoparticles by DHA-treated cancer cells examined by surface enhanced Raman spectroscopy in a microfluidic chip. Lab on a Chip. 2017; 17: 1306-1313.

(15)

Fengqiu Zhang, Qing Huang*, Jingwen Yan, and Zhu Chen. Histone acetylation induced transformation of B-DNA to Z-DNA in cells probed through FTIR spectroscopy. Analytical Chemistry. 2016; 88(8): 4179–4182.

(16)

Fengqiu Zhang, Qing Huang*, Jingwen Yan, Xin Zhang, Jianxin Li. Assessment of the effect of Trichostatin A on HeLa cells through FTIR spectroscopy. Analytical Chemistry. 2015; 87: 2511−2517.

(17)

Qing Huang*, Zhulin Huang, Guowen Meng, Yi Fu, Joseph R. Lakowicz. Plasmonic Nanorod Arrays for Enhancement of Single-Molecule Detection. Chemical Communications. 2013; 49: 11743-11745.

(18)

Haibin Tang, Guowen Meng*, Qing Huang*, Zhuo Zhang, Zhulin Huang, Chuhong Zhu. Arrays of Cone-shaped ZnO-NRs Decorated with Ag-NPs as 3D SERS Substrates for Rapid Detection of Trace PCB-77. Advanced Functional Materials. 2011; 22: 218-224.

(19)

Zhigang Ke, Qing Huang*, Hong Zhang, Zeliang Yu, Reduction and Removal of Aqueous Cr(VI) by Glow Discharge Plasma at the Gas-Solution Interface. Environmental Science & Technology. 2011; 45: 7841-7847.

(20)

Qing Huang, Q.G. Huang, R. Pinto, K. Griebenow, R. Schweitzer-Stenner and W.J. Weber. Jr. Inactivation of Horseradish Peroxidase by Phenoxyl Radical Attack. Journal of the American Chemical Society. 2005; 127: 1431-1437.

2.

专利

(1)

黄青;方草;于振海;汪涵;付志英;采用高压放电等离子体增强低压隔膜电解制备眼镜片消毒液的方法,2022-12-29,CN202211704526.9

(2)

黄青;刘超;一种MXene基纳米氧化酶、制备方法及其在检测汞离子中的应用,2022-11-24,CN202211481157.1

(3)

黄青;许航博;刘超;一种采用等离子体射流装置处理水体中有毒真菌及其毒素的方法,2022-11-19,CN202211198436.7

(4)

黄青;刘超;一种自组装柔性 SERS 基底的制备方法及其在农残检测中的应用,2022-10-20, CN202210203820.5

(5)

黄青;郑鑫鑫;一种评价虾青素抗光照氧化能力的方法,2022-06-09,CN202210689692.X

(6)

黄青;梁超;方草;一种分步调节磁场辅助速冻保鲜方法及装置,2022-04-28, CN202210857169.3

(7)

黄青;刘超;王儒敬;余立祥;磁性纳米模拟酶的制备方法、制得的模拟酶及在检测汞离子中的应用,2021-12-20,CN202111564208.2

(8)

黄青;李腊梅;陈祝;一种外加添加剂提高雨生红球藻虾青素产量的方法,2020-03-20, CN202010696872.1

(9)

黄青;刘超;赵云梦;灵芝多糖还原氧化石墨烯制备纳米酶的方法、制得的纳米酶及其应用,2020-11-25,CN202011346635.9

(10)

黄青;刘超;赵云梦;方草石墨烯抗菌复合膜的制备方法、制得的抗菌复合膜,2020-11-25, CN202011346633.X

(11)

黄青;张倩倩;一种基于 NIR 光谱定量测定灵芝子实体中总三萜的方法,2020-07-01, CN202010701566.2

(12)

黄青;马玉涵;何华奇;一种灵芝多糖高产菌株 RWHBW-1 及其应用,2019-02-01,CN201910120979.9

(13)

黄青;闫彬;朱储红;穆罕默德;阶梯式改变氧化电位制备纳米锥阵 SERS 基底的方法,2018-07-31,CN201810846762.1

(14)

黄青;张群霞;陈祝;柯志刚;一种基于等离子体协同助剂的杀菌方法,2018-06-13, CN201811613239.0

(15)

黄青;马玉涵;何华奇;姚国华利用等离子体诱变灵芝原生质体以构建突变菌株的方法,2017-05-31,CN201710418337.

(16)

黄青;王纯阳;单粒稻谷种子的蛋白质定量分析 NIR 透射光谱测量方法,2017-01-05,CN201710028806.5

(17)

黄青;吴茜冉;张启富;污水处理方法,2018-07-17,CN201810778682.7

(18)

黄青;王纯阳;一种基于光谱比例扣除法的稻谷近红外光谱模型优化方法,2016-09-06,CN201610802820.1

(19)

黄青;孙克喜;一种透明 SERS 衬底及微流控芯片、制备方法和应用,2015-10-10,CN201510909432.9

(20)

黄青;孙克喜;孟国文;一种 DNA 芯片及其检测方法与制作方法,2015-07-22,CN201510437983.X

(21)

黄青;李腊梅;张宏;介质阻挡放电等离子体高效处理含藻污水的装置,2014-07-17, CN201420397458.0

(22)

黄青;鲁逸林;一种可以定量检测多氯联苯的表面增强拉曼光谱方法. 2013-11-22,CN201310589987.0

(23)

黄青;柯志刚;余增亮; 一种利用荧光蛋白作为荧光探针测量电离辐射下细胞氧化胁迫损伤的方法,2011-10-07,CN201110079510.9

(24)

黄青;苏玺;柯志刚;余增亮; 一种制备红外固体薄膜样品的新方法用以解决光谱定量评估离子辐射损伤的问题. 2009-10-14,CN200910144907.4

3.

承担项目                

(1)

生物气溶胶智能化防控装备研制及临床集成技术研究,子课题:冷等离子体气溶胶消杀机理及关键技术研究,国家科技重大专项,2025.12—2028.12                 

(2)

MXene基纳米酶近红外光催化促进伤口愈合的应用及机理研究,中国科学院科技合作专项/国际交流计划,2025.1—2026.12                

(3)

基于SERS研究细胞代谢状态及其对PD-L1免疫标志物的影响,国际合作项目,2024.1.1-2026.12.31                

(4)

低温等离子体处理养殖废水中的抗生素,安徽省重点研究与开发计划,2020.1.1—2022.12.30               

(5)

低温等离子体刺激雨生红球藻促产虾青素的效应及机理研究,国家自然科学基金面上项目,2018.1.1—2021.12.31

(6)

载能粒子辐射生物效应的理化基础及早期生物过程研究,国家自然科学基金重点项目,2017.1.1—2021.12.31

(7)

荷能粒子对微藻作用机理及诱变株筛选方法的研究, 国家自然科学基金面上项目,2015.1.1—2018.12.31

(8)

基于表面增强拉曼光谱研究荷能离子对生物分子的辐解作用,国家自然科学基金面上项目 2012.1.1—2015.12.31

(9)

离子注入模式蛋白酶引起构象和功能改变的机理研究,国家自然科学基金面上项目2010.1.1—2012.12.31

(10)

应用生物光谱研究离子辐射与生物体相互作用,中国科学院人才计划项目,2009.1.1—2012.12.31

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